Exome sequencing is a capture based method developed to identify variants in the coding region of genes which affect protein function. While exome capture methods using PCR, hybrid capture and molecular inversion probes exist, the most common and efficient strategies are in-solution capture methods. In-solution capture utilizes pools of oligonucleotides or probes bound to magnetic beads, whose sequence has been designed to hybridize to exon regions. After binding to genomic DNA, these probes are pulled down and washed, allowing exon regions to be selectively sequenced.
While there are approximately 180,000 exons in the human genome, constituting less than 2% of total sequence, the exome contains ~80-90% of known disease causing variants making it a cost-effective alternative to whole genome sequencing. When performing exome-seq, users should not only consider average on-target coverage but also the local coverage of particular sites of interest. When choosing between exome and whole genome sequencing (WGS), consider that exome sequencing has the advantage that oligonucleotides are designed to particular genomic regions where typical coverage with WGS is not enough for SNP calling. It is also more affordable enabling the analysis of more individuals and populations. With WGS, you can detect variants in regions not covered by exome capture allowing or the identification of structural and non-coding variants associated with disease.
The consumption of whole exome sequencing has exceeded 120 K samples per year. Whole exome sequencing is mainly produced by American companies. Mainly largest producers in the world are located in US.
The demand of whole exome sequencing service is very strong in Chinese market, especially in Beijing, Guangzhou and Shanghai. These cities have become the fastest-growing areas, because these cities continue to improve basic health care and scientific research.
According to this study, over the next five years the Whole Exome Sequencing market will register a 14.8% CAGR in terms of revenue, the global market size will reach US$ 400 million by 2024, from US$ 180 million in 2019. In particular, this report presents the global revenue market share of key companies in Whole Exome Sequencing business, shared in Chapter 3.
This report presents a comprehensive overview, market shares, and growth opportunities of Whole Exome Sequencing market by product type, application, key manufacturers and key regions and countries.
This study considers the Whole Exome Sequencing value generated from the sales of the following segments:
Segmentation by product type:
Agilent HaloPlex
Agilent SureSelect
Illumina TruSeq Exome
Roche Nimblegen SeqCap
MYcroarray MYbaits
Segmentation by application:
Correlation Research of Normal Human
Mendelian Disease and Rare Syndrome Gene Discovery
The Research of Complex Diseases
Mouse Exome Sequencing
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
The report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the market. The key manufacturers covered in this report:
Illumina
Thermo Fisher
Roche
Angilent
Eurofins
Sengenics
Ambry
Macrogen
BGI
Novo Gene
In addition, this report discusses the key drivers influencing market growth, opportunities, the challenges and the risks faced by key players and the market as a whole. It also analyzes key emerging trends and their impact on present and future development.
Research objectives
To study and analyze the global Whole Exome Sequencing market size by key regions/countries, product type and application.
To understand the structure of Whole Exome Sequencing market by identifying its various subsegments.
Focuses on the key global Whole Exome Sequencing players, to define, describe and analyze the value, market share, market competition landscape, SWOT analysis and development plans in next few years.
To analyze the Whole Exome Sequencing with respect to individual growth trends, future prospects, and their contribution to the total market.
To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).
To project the size of Whole Exome Sequencing submarkets, with respect to key regions (along with their respective key countries).
To analyze competitive developments such as expansions, agreements, new product launches and acquisitions in the market.
To strategically profile the key players and comprehensively analyze their growth strategies.
The base year for the study has been considered 2019, historic year 2014 and 2018, the forecast period considered is from 2020 to 2027. The regions analyzed for the market include North America, Europe, South America, Asia Pacific, and Middle East and Africa. These regions are further analyzed at the country-level. The study also includes attractiveness analysis of type, application and regions which are benchmarked based on their market size, growth rate and attractiveness in terms of present and future opportunity for understanding the future growth of the market.
Market is segmented on the basis:
The report offers in-depth analysis of driving factors, opportunities, restraints, and challenges for gaining the key insight of the market. The report emphasizes on all the key trends that play a vital role in the enlargement of the market from 2019 to 2026.
The report provides company profile of the key players operating in the market and a comparative analysis based on their business overviews industry offering, segment market share, regional presence, business strategies, innovations, mergers & acquisitions, recent developments, joint venture, collaborations, partnerships, SWOT analysis, and key financial information.
Table of Contents
2019-2024 Global Whole Exome Sequencing Market Report (Status and Outlook)
1 Scope of the Report
1.1 Market Introduction
1.2 Research Objectives
1.3 Years Considered
1.4 Market Research Methodology
1.5 Economic Indicators
1.6 Currency Considered
2 Executive Summary
2.1 World Market Overview
2.1.1 Global Whole Exome Sequencing Market Size 2019-2024
2.1.2 Whole Exome Sequencing Market Size CAGR by Region
2.2 Whole Exome Sequencing Segment by Type
2.2.1 Agilent HaloPlex
2.2.2 Agilent SureSelect
2.2.3 Agilent SureSelect QXT
2.2.4 Illumina TruSeq Exome
2.2.5 Roche Nimblegen SeqCap
2.2.6 MYcroarray MYbaits
2.3 Whole Exome Sequencing Market Size by Type
2.3.1 Global Whole Exome Sequencing Market Size Market Share by Type (2019-2024)
2.3.2 Global Whole Exome Sequencing Market Size Growth Rate by Type (2019-2024)
2.4 Whole Exome Sequencing Segment by Application
2.4.1 Correlation Research of Normal Human
2.4.2 Mendelian Disease and Rare Syndrome Gene Discovery
2.4.3 The Research of Complex Diseases
2.4.4 Mouse Exome Sequencing
2.5 Whole Exome Sequencing Market Size by Application
2.5.1 Global Whole Exome Sequencing Market Size Market Share by Application (2019-2024)
2.5.2 Global Whole Exome Sequencing Market Size Growth Rate by Application (2019-2024)
3 Whole Exome Sequencing Key Players
3.1 Date of Key Players Enter into Whole Exome Sequencing
3.2 Key Players Whole Exome Sequencing Product Offered
3.3 Key Players Whole Exome Sequencing Funding/Investment Analysis
3.4 Funding/Investment
3.4.1 Funding/Investment by Regions
3.4.2 Funding/Investment by End Industry
3.5 Key Players Whole Exome Sequencing Valuation & Market Capitalization
3.6 Key Players Mergers & Acquisitions, Expansion Plans
3.7 Market Ranking
3.8 New Product/Technology Launches
3.9 Partnerships, Agreements, and Collaborations
3.10 Mergers and Acquisitions
4 Whole Exome Sequencing by Regions
4.1 Whole Exome Sequencing Market Size by Regions
4.2 Americas Whole Exome Sequencing Market Size Growth
4.3 APAC Whole Exome Sequencing Market Size Growth
4.4 Europe Whole Exome Sequencing Market Size Growth
5 Americas
5.1 Americas Whole Exome Sequencing Market Size by Countries
5.2 Americas Whole Exome Sequencing Market Size by Type
5.3 Americas Whole Exome Sequencing Market Size by Application
5.4 United States
5.5 Canada
5.6 Mexico
5.7 Key Economic Indicators of Few Americas Countries
6 APAC
6.1 APAC Whole Exome Sequencing Market Size by Countries
6.2 APAC Whole Exome Sequencing Market Size by Type
6.3 APAC Whole Exome Sequencing Market Size by Application
6.4 China
6.5 Japan
6.6 Korea
6.7 Southeast Asia
6.8 India
6.9 Australia
6.10 Key Economic Indicators of Few APAC Countries
7 Europe
7.1 Europe Whole Exome Sequencing by Countries
7.2 Europe Whole Exome Sequencing Market Size by Type
7.3 Europe Whole Exome Sequencing Market Size by Application
7.4 Germany
7.5 France
7.6 UK
7.7 Italy
7.8 Russia
7.9 Key Economic Indicators of Few Europe Countries
8 Market Drivers, Challenges and Trends
8.1 Market Drivers and Impact
8.1.1 Growing Demand from Key Regions
8.1.2 Growing Demand from Key Applications and Potential Industries
8.2 Market Challenges and Impact
8.3 Market Trends
8.4 Market Ecosystem and Roles
9 Key Investors in Whole Exome Sequencing
9.1 Company A
9.1.1 Company A Company Details
9.1.2 Company Description
9.1.3 Companies Invested by Company A
9.1.4 Company A Key Development and Market Layout
9.2 Company B
9.2.1 Company B Company Details
9.2.2 Company Description
9.2.3 Companies Invested by Company B
9.2.4 Company B Key Development and Market Layout
9.3 Company C
9.3.1 Company C Company Details
9.3.2 Company Description
9.3.3 Companies Invested by Company C
9.3.4 Company C Key Development and Market Layout
9.4 Company D
9.4.1 Company D Company Details
9.4.2 Company Description
9.4.3 Companies Invested by Company D
9.4.4 Company D Key Development and Market Layout
…
10 Key Players Analysis
10.1 Illumina
10.1.1 Company Details
10.1.2 Whole Exome Sequencing Product Offered
10.1.3 Illumina Whole Exome Sequencing Market Size
10.1.4 Main Business Overview
10.1.5 Illumina News
10.2 Thermo Fisher
10.2.1 Company Details
10.2.2 Whole Exome Sequencing Product Offered
10.2.3 Thermo Fisher Whole Exome Sequencing Market Size
10.2.4 Main Business Overview
10.2.5 Thermo Fisher News
10.3 Roche
10.3.1 Company Details
10.3.2 Whole Exome Sequencing Product Offered
10.3.3 Roche Whole Exome Sequencing Market Size
10.3.4 Main Business Overview
10.3.5 Roche News
10.4 Angilent
10.4.1 Company Details
10.4.2 Whole Exome Sequencing Product Offered
10.4.3 Angilent Whole Exome Sequencing Market Size
10.4.4 Main Business Overview
10.4.5 Angilent News
10.5 Eurofins
10.5.1 Company Details
10.5.2 Whole Exome Sequencing Product Offered
10.5.3 Eurofins Whole Exome Sequencing Market Size
10.5.4 Main Business Overview
10.5.5 Eurofins News
10.6 Sengenics
10.6.1 Company Details
10.6.2 Whole Exome Sequencing Product Offered
10.6.3 Sengenics Whole Exome Sequencing Market Size
10.6.4 Main Business Overview
10.6.5 Sengenics News
10.7 Ambry
10.7.1 Company Details
10.7.2 Whole Exome Sequencing Product Offered
10.7.3 Ambry Whole Exome Sequencing Market Size
10.7.4 Main Business Overview
10.7.5 Ambry News
10.8 Macrogen
10.8.1 Company Details
10.8.2 Whole Exome Sequencing Product Offered
10.8.3 Macrogen Whole Exome Sequencing Market Size
10.8.4 Main Business Overview
10.8.5 Macrogen News
10.9 BGI
10.9.1 Company Details
10.9.2 Whole Exome Sequencing Product Offered
10.9.3 BGI Whole Exome Sequencing Market Size
10.9.4 Main Business Overview
10.9.5 BGI News
10.10 Novo Gene
10.10.1 Company Details
10.10.2 Whole Exome Sequencing Product Offered
10.10.3 Novo Gene Whole Exome Sequencing Market Size
10.10.4 Main Business Overview
10.10.5 Novo Gene News
11 Research Findings and Conclusion
List of Tables and Figures
Figure Picture of Whole Exome Sequencing
Figure Whole Exome Sequencing Report Years Considered
Figure Market Research Methodology
Figure Global