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Liver is a vital organ that performs several important bodily functions including bile production for digestion, protein production, synthesis of blood clotting factors, storage of glucose (sugar) in the form glycogen, and detoxification. Also, the liver cells have a remarkable ability to regenerate themselves after any damage. Due to this unique capability, the liver tissues have fascinated the researchers. True understanding of molecular and cellular connectivity and functions of the liver tissues in an in-vivo as well as in-vitro setting is very important from the viewpoint of discovery science and clinical application. Development of liver models that can provide a virtual ecosystem that mimics the molecular processes of a liver factory can help understand molecular interactions to network dynamics and whole organ functions. These advanced liver models are mini-organs or organoids that are expected to replicate human liver physiology, anatomy, and functions from molecular layer upward. The formation of these living models is a fairly new area of science that has the potential to replace animal models. The human liver models offer several advantages over animal models that are not always accurate and pose ethical issues. The human liver models or organoids have been used to screen new drugs for liver toxicity. These models are also being deeply studied to build a functional model of human liver development. The process of making a human liver model starts with a fetal liver progenitor cell, an immature cell that transforms into a specialized liver cell. The fetal liver progenitor cell is allowed to self-assemble in a small disc. These discs are composed of ferret liver cells that are pre-processed to remove all cells of the ferret. The resultant mini-organ models the actual human liver development. These models have been observed to generate hepatocytes, the basic functional cells of the liver, which is expected to produce the functional bioengineered liver tissues for transplantation into patients in the near future.
Scope of the Report:
This report focuses on the Human Liver Models in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
North American segment accounted for the largest share of the market in 2018. The human liver market for North America is driven by the presence of a well-established life sciences industry, growing awareness about the organoids technology, increasing government funding, growing incidence of NAFLD, and unavailability of livers for transplantation, increasing investments on research, rising focus on tissue culture-based clinical diagnostics, and the availability of skilled professionals.
The worldwide market for Human Liver Models is expected to grow at a CAGR of roughly xx% over the next five years, will reach xx million US$ in 2023, from xx million US$ in 2017, according to a new GIR (Global Info Research) study.
Market Segment by Manufacturers, this report covers
Emulate
Ascendance Bio
InSphero
CN Bio
Organovo
Cyfuse Biomedical
Mimetas
Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
Liver Organoids
Liver-on-a-chip
2D Models
3D Bioprinting
Others
Market Segment by Applications, can be divided into
Drug Discovery
Education
Others
There are 15 Chapters to deeply display the global Human Liver Models market.
Chapter 1, to describe Human Liver Models Introduction, product scope, market overview, market opportunities, market risk, market driving force;
Chapter 2, to analyze the top manufacturers of Human Liver Models, with sales, revenue, and price of Human Liver Models, in 2016 and 2017;
Chapter 3, to display the competitive situation among the top manufacturers, with sales, revenue and market share in 2016 and 2017;
Chapter 4, to show the global market by regions, with sales, revenue and market share of Human Liver Models, for each region, from 2013 to 2018;
Chapter 5, 6, 7, 8 and 9, to analyze the market by countries, by type, by application and by manufacturers, with sales, revenue and market share by key countries in these regions;
Chapter 10 and 11, to show the market by type and application, with sales market share and growth rate by type, application, from 2013 to 2018;
Chapter 12, Human Liver Models market forecast, by regions, type and application, with sales and revenue, from 2018 to 2023;
Chapter 13, 14 and 15, to describe Human Liver Models sales channel, distributors, traders, dealers, Research Findings and Conclusion, appendix and data source
The base year for the study has been considered 2019, historic year 2014 and 2018, the forecast period considered is from 2020 to 2027. The regions analyzed for the market include North America, Europe, South America, Asia Pacific, and Middle East and Africa. These regions are further analyzed at the country-level. The study also includes attractiveness analysis of type, application and regions which are benchmarked based on their market size, growth rate and attractiveness in terms of present and future opportunity for understanding the future growth of the market.
Market is segmented on the basis:
The report offers in-depth analysis of driving factors, opportunities, restraints, and challenges for gaining the key insight of the market. The report emphasizes on all the key trends that play a vital role in the enlargement of the market from 2019 to 2026.
The report provides company profile of the key players operating in the market and a comparative analysis based on their business overviews industry offering, segment market share, regional presence, business strategies, innovations, mergers & acquisitions, recent developments, joint venture, collaborations, partnerships, SWOT analysis, and key financial information.
Table of Contents
1 Market Overview
1.1 Human Liver Models Introduction
1.2 Market Analysis by Type
1.2.1 Liver Organoids
1.2.2 Liver-on-a-chip
1.2.3 2D Models
1.2.4 3D Bioprinting
1.2.5 Others
1.3 Market Analysis by Applications
1.3.1 Drug Discovery
1.3.2 Education
1.3.3 Others
1.4 Market Analysis by Regions
1.4.1 North America (United States, Canada and Mexico)
1.4.1.1 United States Market States and Outlook (2013-2023)
1.4.1.2 Canada Market States and Outlook (2013-2023)
1.4.1.3 Mexico Market States and Outlook (2013-2023)
1.4.2 Europe (Germany, France, UK, Russia and Italy)
1.4.2.1 Germany Market States and Outlook (2013-2023)
1.4.2.2 France Market States and Outlook (2013-2023)
1.4.2.3 UK Market States and Outlook (2013-2023)
1.4.2.4 Russia Market States and Outlook (2013-2023)
1.4.2.5 Italy Market States and Outlook (2013-2023)
1.4.3 Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
1.4.3.1 China Market States and Outlook (2013-2023)
1.4.3.2 Japan Market States and Outlook (2013-2023)
1.4.3.3 Korea Market States and Outlook (2013-2023)
1.4.3.4 India Market States and Outlook (2013-2023)
1.4.3.5 Southeast Asia Market States and Outlook (2013-2023)
1.4.4 South America, Middle East and Africa
1.4.4.1 Brazil Market States and Outlook (2013-2023)
1.4.4.2 Egypt Market States and Outlook (2013-2023)
1.4.4.3 Saudi Arabia Market States and Outlook (2013-2023)
1.4.4.4 South Africa Market States and Outlook (2013-2023)
1.4.4.5 Nigeria Market States and Outlook (2013-2023)
1.5 Market Dynamics
1.5.1 Market Opportunities
1.5.2 Market Risk
1.5.3 Market Driving Force
2 Manufacturers Profiles
2.1 Emulate
2.1.1 Business Overview
2.1.2 Human Liver Models Type and Applications
2.1.2.1 Product A
2.1.2.2 Product B
2.1.3 Emulate Human Liver Models Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.2 Ascendance Bio
2.2.1 Business Overview
2.2.2 Human Liver Models Type and Applications
2.2.2.1 Product A
2.2.2.2 Product B
2.2.3 Ascendance Bio Human Liver Models Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.3 InSphero
2.3.1 Business Overview
2.3.2 Human Liver Models Type and Applications
2.3.2.1 Product A
2.3.2.2 Product B
2.3.3 InSphero Human Liver Models Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.4 CN Bio
2.4.1 Business Overview
2.4.2 Human Liver Models Type and Applications
2.4.2.1 Product A
2.4.2.2 Product B
2.4.3 CN Bio Human Liver Models Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.5 Organovo
2.5.1 Business Overview
2.5.2 Human Liver Models Type and Applications
2.5.2.1 Product A
2.5.2.2 Product B
2.5.3 Organovo Human Liver Models Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.6 Cyfuse Biomedical
2.6.1 Business Overview
2.6.2 Human Liver Models Type and Applications
2.6.2.1 Product A
2.6.2.2 Product B
2.6.3 Cyfuse Biomedical Human Liver Models Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.7 Mimetas
2.7.1 Business Overview
2.7.2 Human Liver Models Type and Applications
2.7.2.1 Product A
2.7.2.2 Product B
2.7.3 Mimetas Human Liver Models Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
3 Global Human Liver Models Sales, Revenue, Market Share and Competition by Manufacturer (2016-2017)
3.1 Global Human Liver Models Sales and Market Share by Manufacturer (2016-2017)
3.2 Global Human Liver Models Revenue and Market Share by Manufacturer (2016-2017)
3.3 Market Concentration Rate
3.3.1 Top 3 Human Liver Models Manufacturer Market Share in 2017
3.3.2 Top 6 Human Liver Models Manufacturer Market Share in 2017
3.4 Market Competition Trend
4 Global Human Liver Models Market Analysis by Regions
4.1 Global Human Liver Models Sales, Revenue and Market Share by Regions
4.1.1 Global Human Liver Models Sales and Market Share by Regions (2013-2018)
4.1.2 Global Human Liver Models Revenue and Market Share by Regions (2013-2018)
4.2 North America Human Liver Models Sales and Growth Rate (2013-2018)
4.3 Europe Human Liver Models Sales and Growth Rate (2013-2018)
4.4 Asia-Pacific Human Liver Models Sales and Growth Rate (2013-2018)
4.5 South America Human Liver Models Sales and Growth Rate (2013-2018)
4.6 Middle East and Africa Human Liver Models Sales and Growth Rate (2013-2018)
5 North America Human Liver Models by Countries
5.1 North America Human Liver Models Sales, Revenue and Market Share by Countries
5.1.1 North America Human Liver Models Sales and Market Share by Countries (2013-2018)
5.1.2 North America Human Liver Models Revenue and Market Share by Countries (2013-2018)
5.2 United States Human Liver Models Sales and Growth Rate (2013-2018)
5.3 Canada Human Liver Models Sales and Growth Rate (2013-2018)
5.4 Mexico Human Liver Models Sales and Growth Rate (2013-2018)
6 Europe Human Liver Models by Countries
6.1 Europe Human Liver Models Sales, Revenue and Market Share by Countries
6.1.1 Europe Human Liver Models Sales and Market Share by Countries (2013-2018)
6.1.2 Europe Human Liver Models Revenue and Market Share by Countries (2013-2018)
6.2 Germany Human Liver Models Sales and Growth Rate (2013-2018)
6.3 UK Human Liver Models Sales and Growth Rate (2013-2018)
6.4 France Human Liver Models Sales and Growth Rate (2013-2018)
6.5 Russia Human Liver Models Sales and Growth Rate (2013-2018)
6.6 Italy Human Liver Models Sales and Growth Rate (2013-2018)
7 Asia-Pacific Human Liver Models by Countries
7.1 Asia-Pacific Human Liver Models Sales, Revenue and Market Share by Countries
7.1.1 Asia-Pacific Human Liver Models Sales and Market Share by Countries (2013-2018)
7.1.2 Asia-Pacific Human Liver Models Revenue and Market Share by Countries (2013-2018)
7.2 China Human Liver Models Sales and Growth Rate (2013-2018)
7.3 Japan Human Liver Models Sales and Growth Rate (2013-2018)
7.4 Korea Human Liver Models Sales and Growth Rate (2013-2018)
7.5 India Human Liver Models Sales and Growth Rate (2013-2018)
7.6 Southeast Asia Human Liver Models Sales and Growth Rate (2013-2018)
8 South America Human Liver Models by Countries
8.1 South America Human Liver Models Sales, Revenue and Market Share by Countries
8.1.1 South America Human Liver Models Sales and Market Share by Countries (2013-2018)
8.1.2 South America Human Liver Models Revenue and Market Share by Countries (2013-2018)
8.2 Brazil Human Liver Models Sales and Growth Rate (2013-2018)
8.3 Argentina Human Liver Models Sales and Growth Rate (2013-2018)
8.4 Colombia Human Liver Models Sales and Growth Rate (2013-2018)
9 Middle East and Africa Human Liver Models by Countries
9.1 Middle East and Africa Human Liver Models Sales, Revenue and Market Share by Countries
9.1.1 Middle East and Africa Human Liver Models Sales and Market Share by Countries (2013-2018)
9.1.2 Middle East and Africa Human Liver Models Revenue and Market Share by Countries (2013-2018)
9.2 Saudi Arabia Human Liver Models Sales and Growth Rate (2013-2018)
9.3 UAE Human Liver Models Sales and Growth Rate (2013-2018)
9.4 Egypt Human Liver Models Sales and Growth Rate (2013-2018)
9.5 Nigeria Human Liver Models Sales and Growth Rate (2013-2018)
9.6 South Africa Human Liver Models Sales and Growth Rate (2013-2018)
10 Global Human Liver Models Market Segment by Type
10.1 Global Human Liver Models Sales, Revenue and Market Share by Type (2013-2018)
10.1.1 Global Human Liver Models Sales and Market Share by Type (2013-2018)
10.1.2 Global Human Liver Models Revenue and Market Share by Type (2013-2018)
10.2 Liver Organoids Sales Growth and Price
10.2.1 Global Liver Organoids Sales Growth (2013-2018)
10.2.2 Global Liver Organoids Price (2013-2018)
10.3 Liver-on-a-chip Sales Growth and Price
10.3.1 Global Liver-on-a-chip Sales Growth (2013-2018)
10.3.2 Global Liver-on-a-chip Price (2013-2018)
10.4 2D Models Sales Growth and Price
10.4.1 Global 2D Models Sales Growth (2013-2018)
10.4.2 Global 2D Models Price (2013-2018)
10.5 3D Bioprinting Sales Growth and Price
10.5.1 Global 3D Bioprinting Sales Growth (2013-2018)
10.5.2 Global 3D Bioprinting Price (2013-2018)
10.6 Others Sales Growth and Price
10.6.1 Global Others Sales Growth (2013-2018)
10.6.2 Global Others Price (2013-2018)
11 Global Human Liver Models Market Segment by Application
11.1 Global Human Liver Models Sales Market Share by Application (2013-2018)
11.2 Drug Discovery Sales Growth (2013-2018)
11.3 Education Sales Growth (2013-2018)
11.4 Others Sales Growth (2013-2018)
12 Human Liver Models Market Forecast (2018-2023)
12.1 Global Human Liver Models Sales, Revenue and Growth Rate (2018-2023)
12.2 Human Liver Models Market Forecast by Regions (2018-2023)
12.2.1 North America Human Liver Models Market Forecast (2018-2023)
12.2.2 Europe Human Liver Models Market Forecast (2018-2023)
12.2.3 Asia-Pacific Human Liver Models Market Forecast (2018-2023)
12.2.4 South America Human Liver Models Market Forecast (2018-2023)
12.2.5 Middle East and Africa Human Liver Models Market Forecast (2018-2023)
12.3 Human Liver Models Market Forecast by Type (2018-2023)
12.3.1 Global Human Liver Models Sales Forecast by Type (2018-2023)
12.3.2 Global Human Liver Models Market Share Forecast by Type (2018-2023)
12.4 Human Liver Models Market Forecast by Application (2018-2023)
12.4.1 Global Human Liver Models Sales Forecast by Application (2018-2023)
12.4.2 Global Human Liver Models Market Share Forecast by Application (2018-2023)
13 Sales Channel, Distributors, Traders and Dealers
13.1 Sales Channel
13.1.1 Direct Marketing
13.1.2 Indirect Marketing
13.1.3 Marketing Channel Future Trend
13.2 Distributors, Traders and Dealers
14 Research Findings and Conclusion
15 Appendix
15.1 Methodology
15.2 Data Source
List of Tables and Figures
Figure Human Liver Models Picture
Table Product Specifications of Human Liver Models
Figure Global Sales Market Share of Human Liver Models by Types in 2017
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