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c-Met is a proto-oncogene responsible for encoding the high-affinity receptor for hepatocyte growth factor (HGF). Hepatocyte growth factor is also known as scatter factor which participates in HGF/c-MET signaling pathway. This pathway plays vital role in mitogenesis and morphogenesis during embryonic development and wound healing. The controlled natural activity of c-Met and HGF is important in mammalian development, tissue maintenance, and repair. Binding of HGF to c-MET receptor induces several biological responses collectively known as invasive growth program. These responses are elicited due to activation of several pathways such as RAS pathway, PI3K pathway, STAT pathway, beta-catenin pathway and Notch pathway. However, dysregulation of the HGF/c-MET signaling pathway has been associated with the progression of cancers through activation of oncogenic pathways, angiogenesis and metastasis.
Scope of the Report:
This report focuses on the C-MET / HGF Inhibitors in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
The major cancers such as breast, colon and non-small-cell lung carcinoma (NSCLC) are being examined for efficacy with c-MET / HGF inhibitors. Several small molecule c-Met kinase inhibitors have demonstrated clinical efficacy in cancer treatment and many clinical trials are underway. However, as the small molecule inhibitors lack specificity or selectivity they can cause toxicity. Therefore, researchers are increasing focus to develop antibody therapeutics against c-Met or HGF.
The worldwide market for C-MET / HGF Inhibitors is expected to grow at a CAGR of roughly xx% over the next five years, will reach xx million US$ in 2023, from xx million US$ in 2017, according to a new GIR (Global Info Research) study.
Market Segment by Manufacturers, this report covers
Abxign
Abbott Laboratories
Amgen
ArQule
Astex Therapeutics
AVEO Pharmaceuticals
Bristol-Myers Squibb(BMS)
Chroma Therapeutics
Daiichi Sankyo
Deciphera Pharmaceuticals
Eisai
Eli Lilly
Exelixis
Genmab
Galaxy Biotech
GlaxoSmithKline(GSK)
Hutchison MediPharma
Johnson & Johnson
Kringle Pharmaceuticals
Merck
Methylgene
Novartis
Pfizer
ProMetic BioTherapeutics
Takeda Pharmaceutical
Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
C-Met Biologic Inhibitors
Small Molecule C-Met Inhibitors
HGF Antagonist Antibodies
C-Met Antagonist Antibodies(MetMAb)
HGF Kringle Variant Antagonists
Market Segment by Applications, can be divided into
Hospital Pharmacies
Retail Pharmacies
Drug Stores
Online Sales
There are 15 Chapters to deeply display the global C-MET / HGF Inhibitors market.
Chapter 1, to describe C-MET / HGF Inhibitors Introduction, product scope, market overview, market opportunities, market risk, market driving force;
Chapter 2, to analyze the top manufacturers of C-MET / HGF Inhibitors, with sales, revenue, and price of C-MET / HGF Inhibitors, in 2016 and 2017;
Chapter 3, to display the competitive situation among the top manufacturers, with sales, revenue and market share in 2016 and 2017;
Chapter 4, to show the global market by regions, with sales, revenue and market share of C-MET / HGF Inhibitors, for each region, from 2013 to 2018;
Chapter 5, 6, 7, 8 and 9, to analyze the market by countries, by type, by application and by manufacturers, with sales, revenue and market share by key countries in these regions;
Chapter 10 and 11, to show the market by type and application, with sales market share and growth rate by type, application, from 2013 to 2018;
Chapter 12, C-MET / HGF Inhibitors market forecast, by regions, type and application, with sales and revenue, from 2018 to 2023;
Chapter 13, 14 and 15, to describe C-MET / HGF Inhibitors sales channel, distributors, traders, dealers, Research Findings and Conclusion, appendix and data source
The base year for the study has been considered 2019, historic year 2014 and 2018, the forecast period considered is from 2020 to 2027. The regions analyzed for the market include North America, Europe, South America, Asia Pacific, and Middle East and Africa. These regions are further analyzed at the country-level. The study also includes attractiveness analysis of type, application and regions which are benchmarked based on their market size, growth rate and attractiveness in terms of present and future opportunity for understanding the future growth of the market.
Market is segmented on the basis:
The report offers in-depth analysis of driving factors, opportunities, restraints, and challenges for gaining the key insight of the market. The report emphasizes on all the key trends that play a vital role in the enlargement of the market from 2019 to 2026.
The report provides company profile of the key players operating in the market and a comparative analysis based on their business overviews industry offering, segment market share, regional presence, business strategies, innovations, mergers & acquisitions, recent developments, joint venture, collaborations, partnerships, SWOT analysis, and key financial information.
Table of Contents
1 Market Overview
1.1 C-MET / HGF Inhibitors Introduction
1.2 Market Analysis by Type
1.2.1 C-Met Biologic Inhibitors
1.2.2 Small Molecule C-Met Inhibitors
1.2.3 HGF Antagonist Antibodies
1.2.4 C-Met Antagonist Antibodies(MetMAb)
1.2.5 HGF Kringle Variant Antagonists
1.3 Market Analysis by Applications
1.3.1 Hospital Pharmacies
1.3.2 Retail Pharmacies
1.3.3 Drug Stores
1.3.4 Online Sales
1.4 Market Analysis by Regions
1.4.1 North America (United States, Canada and Mexico)
1.4.1.1 United States Market States and Outlook (2013-2023)
1.4.1.2 Canada Market States and Outlook (2013-2023)
1.4.1.3 Mexico Market States and Outlook (2013-2023)
1.4.2 Europe (Germany, France, UK, Russia and Italy)
1.4.2.1 Germany Market States and Outlook (2013-2023)
1.4.2.2 France Market States and Outlook (2013-2023)
1.4.2.3 UK Market States and Outlook (2013-2023)
1.4.2.4 Russia Market States and Outlook (2013-2023)
1.4.2.5 Italy Market States and Outlook (2013-2023)
1.4.3 Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
1.4.3.1 China Market States and Outlook (2013-2023)
1.4.3.2 Japan Market States and Outlook (2013-2023)
1.4.3.3 Korea Market States and Outlook (2013-2023)
1.4.3.4 India Market States and Outlook (2013-2023)
1.4.3.5 Southeast Asia Market States and Outlook (2013-2023)
1.4.4 South America, Middle East and Africa
1.4.4.1 Brazil Market States and Outlook (2013-2023)
1.4.4.2 Egypt Market States and Outlook (2013-2023)
1.4.4.3 Saudi Arabia Market States and Outlook (2013-2023)
1.4.4.4 South Africa Market States and Outlook (2013-2023)
1.4.4.5 Nigeria Market States and Outlook (2013-2023)
1.5 Market Dynamics
1.5.1 Market Opportunities
1.5.2 Market Risk
1.5.3 Market Driving Force
2 Manufacturers Profiles
2.1 Abxign
2.1.1 Business Overview
2.1.2 C-MET / HGF Inhibitors Type and Applications
2.1.2.1 Product A
2.1.2.2 Product B
2.1.3 Abxign C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.2 Abbott Laboratories
2.2.1 Business Overview
2.2.2 C-MET / HGF Inhibitors Type and Applications
2.2.2.1 Product A
2.2.2.2 Product B
2.2.3 Abbott Laboratories C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.3 Amgen
2.3.1 Business Overview
2.3.2 C-MET / HGF Inhibitors Type and Applications
2.3.2.1 Product A
2.3.2.2 Product B
2.3.3 Amgen C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.4 ArQule
2.4.1 Business Overview
2.4.2 C-MET / HGF Inhibitors Type and Applications
2.4.2.1 Product A
2.4.2.2 Product B
2.4.3 ArQule C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.5 Astex Therapeutics
2.5.1 Business Overview
2.5.2 C-MET / HGF Inhibitors Type and Applications
2.5.2.1 Product A
2.5.2.2 Product B
2.5.3 Astex Therapeutics C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.6 AVEO Pharmaceuticals
2.6.1 Business Overview
2.6.2 C-MET / HGF Inhibitors Type and Applications
2.6.2.1 Product A
2.6.2.2 Product B
2.6.3 AVEO Pharmaceuticals C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.7 Bristol-Myers Squibb(BMS)
2.7.1 Business Overview
2.7.2 C-MET / HGF Inhibitors Type and Applications
2.7.2.1 Product A
2.7.2.2 Product B
2.7.3 Bristol-Myers Squibb(BMS) C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.8 Chroma Therapeutics
2.8.1 Business Overview
2.8.2 C-MET / HGF Inhibitors Type and Applications
2.8.2.1 Product A
2.8.2.2 Product B
2.8.3 Chroma Therapeutics C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.9 Daiichi Sankyo
2.9.1 Business Overview
2.9.2 C-MET / HGF Inhibitors Type and Applications
2.9.2.1 Product A
2.9.2.2 Product B
2.9.3 Daiichi Sankyo C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.10 Deciphera Pharmaceuticals
2.10.1 Business Overview
2.10.2 C-MET / HGF Inhibitors Type and Applications
2.10.2.1 Product A
2.10.2.2 Product B
2.10.3 Deciphera Pharmaceuticals C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.11 Eisai
2.11.1 Business Overview
2.11.2 C-MET / HGF Inhibitors Type and Applications
2.11.2.1 Product A
2.11.2.2 Product B
2.11.3 Eisai C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.12 Eli Lilly
2.12.1 Business Overview
2.12.2 C-MET / HGF Inhibitors Type and Applications
2.12.2.1 Product A
2.12.2.2 Product B
2.12.3 Eli Lilly C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.13 Exelixis
2.13.1 Business Overview
2.13.2 C-MET / HGF Inhibitors Type and Applications
2.13.2.1 Product A
2.13.2.2 Product B
2.13.3 Exelixis C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.14 Genmab
2.14.1 Business Overview
2.14.2 C-MET / HGF Inhibitors Type and Applications
2.14.2.1 Product A
2.14.2.2 Product B
2.14.3 Genmab C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.15 Galaxy Biotech
2.15.1 Business Overview
2.15.2 C-MET / HGF Inhibitors Type and Applications
2.15.2.1 Product A
2.15.2.2 Product B
2.15.3 Galaxy Biotech C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.16 GlaxoSmithKline(GSK)
2.16.1 Business Overview
2.16.2 C-MET / HGF Inhibitors Type and Applications
2.16.2.1 Product A
2.16.2.2 Product B
2.16.3 GlaxoSmithKline(GSK) C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.17 Hutchison MediPharma
2.17.1 Business Overview
2.17.2 C-MET / HGF Inhibitors Type and Applications
2.17.2.1 Product A
2.17.2.2 Product B
2.17.3 Hutchison MediPharma C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.18 Johnson & Johnson
2.18.1 Business Overview
2.18.2 C-MET / HGF Inhibitors Type and Applications
2.18.2.1 Product A
2.18.2.2 Product B
2.18.3 Johnson & Johnson C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.19 Kringle Pharmaceuticals
2.19.1 Business Overview
2.19.2 C-MET / HGF Inhibitors Type and Applications
2.19.2.1 Product A
2.19.2.2 Product B
2.19.3 Kringle Pharmaceuticals C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.20 Merck
2.20.1 Business Overview
2.20.2 C-MET / HGF Inhibitors Type and Applications
2.20.2.1 Product A
2.20.2.2 Product B
2.20.3 Merck C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.21 Methylgene
2.21.1 Business Overview
2.2.2 C-MET / HGF Inhibitors Type and Applications
2.21.2.1 Product A
2.21.2.2 Product B
2.21.3 Methylgene C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.22 Novartis
2.22.1 Business Overview
2.22.2 C-MET / HGF Inhibitors Type and Applications
2.22.2.1 Product A
2.22.2.2 Product B
2.22.3 Novartis C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.23 Pfizer
2.23.1 Business Overview
2.23.2 C-MET / HGF Inhibitors Type and Applications
2.23.2.1 Product A
2.23.2.2 Product B
2.23.3 Pfizer C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.24 ProMetic BioTherapeutics
2.24.1 Business Overview
2.24.2 C-MET / HGF Inhibitors Type and Applications
2.24.2.1 Product A
2.24.2.2 Product B
2.24.3 ProMetic BioTherapeutics C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.25 Takeda Pharmaceutical
2.25.1 Business Overview
2.25.2 C-MET / HGF Inhibitors Type and Applications
2.25.2.1 Product A
2.25.2.2 Product B
2.25.3 Takeda Pharmaceutical C-MET / HGF Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
3 Global C-MET / HGF Inhibitors Sales, Revenue, Market Share and Competition by Manufacturer (2016-2017)
3.1 Global C-MET / HGF Inhibitors Sales and Market Share by Manufacturer (2016-2017)
3.2 Global C-MET / HGF Inhibitors Revenue and Market Share by Manufacturer (2016-2017)
3.3 Market Concentration Rate
3.3.1 Top 3 C-MET / HGF Inhibitors Manufacturer Market Share in 2017
3.3.2 Top 6 C-MET / HGF Inhibitors Manufacturer Market Share in 2017
3.4 Market Competition Trend
4 Global C-MET / HGF Inhibitors Market Analysis by Regions
4.1 Global C-MET / HGF Inhibitors Sales, Revenue and Market Share by Regions
4.1.1 Global C-MET / HGF Inhibitors Sales and Market Share by Regions (2013-2018)
4.1.2 Global C-MET / HGF Inhibitors Revenue and Market Share by Regions (2013-2018)
4.2 North America C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
4.3 Europe C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
4.4 Asia-Pacific C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
4.5 South America C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
4.6 Middle East and Africa C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
5 North America C-MET / HGF Inhibitors by Countries
5.1 North America C-MET / HGF Inhibitors Sales, Revenue and Market Share by Countries
5.1.1 North America C-MET / HGF Inhibitors Sales and Market Share by Countries (2013-2018)
5.1.2 North America C-MET / HGF Inhibitors Revenue and Market Share by Countries (2013-2018)
5.2 United States C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
5.3 Canada C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
5.4 Mexico C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
6 Europe C-MET / HGF Inhibitors by Countries
6.1 Europe C-MET / HGF Inhibitors Sales, Revenue and Market Share by Countries
6.1.1 Europe C-MET / HGF Inhibitors Sales and Market Share by Countries (2013-2018)
6.1.2 Europe C-MET / HGF Inhibitors Revenue and Market Share by Countries (2013-2018)
6.2 Germany C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
6.3 UK C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
6.4 France C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
6.5 Russia C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
6.6 Italy C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
7 Asia-Pacific C-MET / HGF Inhibitors by Countries
7.1 Asia-Pacific C-MET / HGF Inhibitors Sales, Revenue and Market Share by Countries
7.1.1 Asia-Pacific C-MET / HGF Inhibitors Sales and Market Share by Countries (2013-2018)
7.1.2 Asia-Pacific C-MET / HGF Inhibitors Revenue and Market Share by Countries (2013-2018)
7.2 China C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
7.3 Japan C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
7.4 Korea C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
7.5 India C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
7.6 Southeast Asia C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
8 South America C-MET / HGF Inhibitors by Countries
8.1 South America C-MET / HGF Inhibitors Sales, Revenue and Market Share by Countries
8.1.1 South America C-MET / HGF Inhibitors Sales and Market Share by Countries (2013-2018)
8.1.2 South America C-MET / HGF Inhibitors Revenue and Market Share by Countries (2013-2018)
8.2 Brazil C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
8.3 Argentina C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
8.4 Colombia C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
9 Middle East and Africa C-MET / HGF Inhibitors by Countries
9.1 Middle East and Africa C-MET / HGF Inhibitors Sales, Revenue and Market Share by Countries
9.1.1 Middle East and Africa C-MET / HGF Inhibitors Sales and Market Share by Countries (2013-2018)
9.1.2 Middle East and Africa C-MET / HGF Inhibitors Revenue and Market Share by Countries (2013-2018)
9.2 Saudi Arabia C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
9.3 UAE C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
9.4 Egypt C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
9.5 Nigeria C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
9.6 South Africa C-MET / HGF Inhibitors Sales and Growth Rate (2013-2018)
10 Global C-MET / HGF Inhibitors Market Segment by Type
10.1 Global C-MET / HGF Inhibitors Sales, Revenue and Market Share by Type (2013-2018)
10.1.1 Global C-MET / HGF Inhibitors Sales and Market Share by Type (2013-2018)
10.1.2 Global C-MET / HGF Inhibitors Revenue and Market Share by Type (2013-2018)
10.2 C-Met Biologic Inhibitors Sales Growth and Price
10.2.1 Global C-Met Biologic Inhibitors Sales Growth (2013-2018)
10.2.2 Global C-Met Biologic Inhibitors Price (2013-2018)
10.3 Small Molecule C-Met Inhibitors Sales Growth and Price
10.3.1 Global Small Molecule C-Met Inhibitors Sales Growth (2013-2018)
10.3.2 Global Small Molecule C-Met Inhibitors Price (2013-2018)
10.4 HGF Antagonist Antibodies Sales Growth and Price
10.4.1 Global HGF Antagonist Antibodies Sales Growth (2013-2018)
10.4.2 Global HGF Antagonist Antibodies Price (2013-2018)
10.5 C-Met Antagonist Antibodies(MetMAb) Sales Growth and Price
10.5.1 Global C-Met Antagonist Antibodies(MetMAb) Sales Growth (2013-2018)
10.5.2 Global C-Met Antagonist Antibodies(MetMAb) Price (2013-2018)
10.6 HGF Kringle Variant Antagonists Sales Growth and Price
10.6.1 Global HGF Kringle Variant Antagonists Sales Growth (2013-2018)
10.6.2 Global HGF Kringle Variant Antagonists Price (2013-2018)
11 Global C-MET / HGF Inhibitors Market Segment by Application
11.1 Global C-MET / HGF Inhibitors Sales Market Share by Application (2013-2018)
11.2 Hospital Pharmacies Sales Growth (2013-2018)
11.3 Retail Pharmacies Sales Growth (2013-2018)
11.4 Drug Stores Sales Growth (2013-2018)
11.5 Online Sales Sales Growth (2013-2018)
12 C-MET / HGF Inhibitors Market Forecast (2018-2023)
12.1 Global C-MET / HGF Inhibitors Sales, Revenue and Growth Rate (2018-2023)
12.2 C-MET / HGF Inhibitors Market Forecast by Regions (2018-2023)
12.2.1 North America C-MET / HGF Inhibitors Market Forecast (2018-2023)
12.2.2 Europe C-MET / HGF Inhibitors Market Forecast (2018-2023)
12.2.3 Asia-Pacific C-MET / HGF Inhibitors Market Forecast (2018-2023)
12.2.4 South America C-MET / HGF Inhibitors Market Forecast (2018-2023)
12.2.5 Middle East and Africa C-MET / HGF Inhibitors Market Forecast (2018-2023)
12.3 C-MET / HGF Inhibitors Market Forecast by Type (2018-2023)
12.3.1 Global C-MET / HGF Inhibitors Sales Forecast by Type (2018-2023)
12.3.2 Global C-MET / HGF Inhibitors Market Share Forecast by Type (2018-2023)
12.4 C-MET / HGF Inhibitors Market Forecast by Application (2018-2023)
12.4.1 Global C-MET / HGF Inhibitors Sales Forecast by Application (2018-2023)
12.4.2 Global C-MET / HGF Inhibitors Market Share Forecast by Application (2018-2023)
13 Sales Channel, Distributors, Traders and Dealers
13.1 Sales Channel
13.1.1 Direct Marketing
13.1.2 Indirect Marketing
13.1.3 Marketing Channel Future Trend
13.2 Distributors, Traders and Dealers
14 Research Findings and Conclusion
15 Appendix
15.1 Methodology
15.2 Data Source
List of Tables and Figures
Figure C-MET / HGF Inhibitors Picture
Table Product Specifications of C-MET / HGF Inhibitors
Figure Global Sales Market Share of C-MET / HGF Inhibitors by Types in 2017
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