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Severe deficiency of alpha-1 antitrypsin (AAT) can cause early-onset emphysema and several liver diseases, including cirrhosis, neonatal hepatitis and hepatocellular carcinoma.
Scope of the Report:
This report focuses on the Alpha 1 Antitrypsin Deficiency Treatment in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
The discovery of the structure and function of the AAT protein and the subsequent isolation and purification thereof have made possible alternative therapies aimed at preventing the progression of related pulmonary diseases (so-called "additional therapies"). The isolation of this gene and the advancement of gene therapy have further increased the possibility of specific treatment. Most specific treatments for AAT deficiency aim to increase plasma AAT levels (and thus elevated AAT concentrations in the interstitial lung) above the protection threshold. Other experimental therapeutic approaches attempt to interfere with the production of abnormal AAT proteins or to inhibit the polymerization of abnormal AAT proteins and to promote the secretion of AAT from hepatocytes. For patients with end-stage lung disease or liver disease, organ transplantation is another treatment option.
Currently, the most direct and effective way to increase AAT levels in plasma and interstitial lung is by intravenous infusion of pooled alpha-1 antitrypsin (pAAT).
The worldwide market for Alpha 1 Antitrypsin Deficiency Treatment is expected to grow at a CAGR of roughly 9.0% over the next five years, will reach 1980 million US$ in 2023, from 1190 million US$ in 2017, according to a new study.
Market Segment by Manufacturers, this report covers
Pfizer
Baxter
AstraZeneca
Grifols
Teva Pharmaceutical Industries
Boehringer Ingelheim
Kamada Ltd
GlaxoSmithKline
CSL Behring
Shire
LFB Biomedicaments
Abeona Therapeutics
Biogen
Applied Genetic Technologies
Baxalta
Arrowhead Research Corporation
ProBioGen
Chiesi Pharmaceuticals
Curaxys
ProMetic Life Sciences
Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
Augmentation Therapy
Bronchodilators
Corticosteroids
Oxygen Therapy
Market Segment by Applications, can be divided into
Hospitals
Specialty Clinics
Pharmacies
There are 15 Chapters to deeply display the global Alpha 1 Antitrypsin Deficiency Treatment market.
Chapter 1, to describe Alpha 1 Antitrypsin Deficiency Treatment Introduction, product scope, market overview, market opportunities, market risk, market driving force;
Chapter 2, to analyze the top manufacturers of Alpha 1 Antitrypsin Deficiency Treatment, with sales, revenue, and price of Alpha 1 Antitrypsin Deficiency Treatment, in 2016 and 2017;
Chapter 3, to display the competitive situation among the top manufacturers, with sales, revenue and market share in 2016 and 2017;
Chapter 4, to show the global market by regions, with sales, revenue and market share of Alpha 1 Antitrypsin Deficiency Treatment, for each region, from 2013 to 2018;
Chapter 5, 6, 7, 8 and 9, to analyze the market by countries, by type, by application and by manufacturers, with sales, revenue and market share by key countries in these regions;
Chapter 10 and 11, to show the market by type and application, with sales market share and growth rate by type, application, from 2013 to 2018;
Chapter 12, Alpha 1 Antitrypsin Deficiency Treatment market forecast, by regions, type and application, with sales and revenue, from 2018 to 2023;
Chapter 13, 14 and 15, to describe Alpha 1 Antitrypsin Deficiency Treatment sales channel, distributors, traders, dealers, Research Findings and Conclusion, appendix and data source
The base year for the study has been considered 2019, historic year 2014 and 2018, the forecast period considered is from 2020 to 2027. The regions analyzed for the market include North America, Europe, South America, Asia Pacific, and Middle East and Africa. These regions are further analyzed at the country-level. The study also includes attractiveness analysis of type, application and regions which are benchmarked based on their market size, growth rate and attractiveness in terms of present and future opportunity for understanding the future growth of the market.
Market is segmented on the basis:
The report offers in-depth analysis of driving factors, opportunities, restraints, and challenges for gaining the key insight of the market. The report emphasizes on all the key trends that play a vital role in the enlargement of the market from 2019 to 2026.
The report provides company profile of the key players operating in the market and a comparative analysis based on their business overviews industry offering, segment market share, regional presence, business strategies, innovations, mergers & acquisitions, recent developments, joint venture, collaborations, partnerships, SWOT analysis, and key financial information.
Table of Contents
1 Market Overview
1.1 Alpha 1 Antitrypsin Deficiency Treatment Introduction
1.2 Market Analysis by Type
1.2.1 Augmentation Therapy
1.2.2 Bronchodilators
1.2.3 Corticosteroids
1.2.4 Oxygen Therapy
1.3 Market Analysis by Applications
1.3.1 Hospitals
1.3.2 Specialty Clinics
1.3.3 Pharmacies
1.4 Market Analysis by Regions
1.4.1 North America (United States, Canada and Mexico)
1.4.1.1 United States Market States and Outlook (2013-2023)
1.4.1.2 Canada Market States and Outlook (2013-2023)
1.4.1.3 Mexico Market States and Outlook (2013-2023)
1.4.2 Europe (Germany, France, UK, Russia and Italy)
1.4.2.1 Germany Market States and Outlook (2013-2023)
1.4.2.2 France Market States and Outlook (2013-2023)
1.4.2.3 UK Market States and Outlook (2013-2023)
1.4.2.4 Russia Market States and Outlook (2013-2023)
1.4.2.5 Italy Market States and Outlook (2013-2023)
1.4.3 Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
1.4.3.1 China Market States and Outlook (2013-2023)
1.4.3.2 Japan Market States and Outlook (2013-2023)
1.4.3.3 Korea Market States and Outlook (2013-2023)
1.4.3.4 India Market States and Outlook (2013-2023)
1.4.3.5 Southeast Asia Market States and Outlook (2013-2023)
1.4.4 South America, Middle East and Africa
1.4.4.1 Brazil Market States and Outlook (2013-2023)
1.4.4.2 Egypt Market States and Outlook (2013-2023)
1.4.4.3 Saudi Arabia Market States and Outlook (2013-2023)
1.4.4.4 South Africa Market States and Outlook (2013-2023)
1.4.4.5 Nigeria Market States and Outlook (2013-2023)
1.5 Market Dynamics
1.5.1 Market Opportunities
1.5.2 Market Risk
1.5.3 Market Driving Force
2 Manufacturers Profiles
2.1 Pfizer
2.1.1 Business Overview
2.1.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.1.2.1 Product A
2.1.2.2 Product B
2.1.3 Pfizer Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.2 Baxter
2.2.1 Business Overview
2.2.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.2.2.1 Product A
2.2.2.2 Product B
2.2.3 Baxter Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.3 AstraZeneca
2.3.1 Business Overview
2.3.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.3.2.1 Product A
2.3.2.2 Product B
2.3.3 AstraZeneca Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.4 Grifols
2.4.1 Business Overview
2.4.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.4.2.1 Product A
2.4.2.2 Product B
2.4.3 Grifols Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.5 Teva Pharmaceutical Industries
2.5.1 Business Overview
2.5.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.5.2.1 Product A
2.5.2.2 Product B
2.5.3 Teva Pharmaceutical Industries Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.6 Boehringer Ingelheim
2.6.1 Business Overview
2.6.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.6.2.1 Product A
2.6.2.2 Product B
2.6.3 Boehringer Ingelheim Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.7 Kamada Ltd
2.7.1 Business Overview
2.7.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.7.2.1 Product A
2.7.2.2 Product B
2.7.3 Kamada Ltd Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.8 GlaxoSmithKline
2.8.1 Business Overview
2.8.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.8.2.1 Product A
2.8.2.2 Product B
2.8.3 GlaxoSmithKline Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.9 CSL Behring
2.9.1 Business Overview
2.9.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.9.2.1 Product A
2.9.2.2 Product B
2.9.3 CSL Behring Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.10 Shire
2.10.1 Business Overview
2.10.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.10.2.1 Product A
2.10.2.2 Product B
2.10.3 Shire Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.11 LFB Biomedicaments
2.11.1 Business Overview
2.11.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.11.2.1 Product A
2.11.2.2 Product B
2.11.3 LFB Biomedicaments Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.12 Abeona Therapeutics
2.12.1 Business Overview
2.12.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.12.2.1 Product A
2.12.2.2 Product B
2.12.3 Abeona Therapeutics Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.13 Biogen
2.13.1 Business Overview
2.13.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.13.2.1 Product A
2.13.2.2 Product B
2.13.3 Biogen Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.14 Applied Genetic Technologies
2.14.1 Business Overview
2.14.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.14.2.1 Product A
2.14.2.2 Product B
2.14.3 Applied Genetic Technologies Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.15 Baxalta
2.15.1 Business Overview
2.15.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.15.2.1 Product A
2.15.2.2 Product B
2.15.3 Baxalta Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.16 Arrowhead Research Corporation
2.16.1 Business Overview
2.16.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.16.2.1 Product A
2.16.2.2 Product B
2.16.3 Arrowhead Research Corporation Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.17 ProBioGen
2.17.1 Business Overview
2.17.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.17.2.1 Product A
2.17.2.2 Product B
2.17.3 ProBioGen Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.18 Chiesi Pharmaceuticals
2.18.1 Business Overview
2.18.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.18.2.1 Product A
2.18.2.2 Product B
2.18.3 Chiesi Pharmaceuticals Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.19 Curaxys
2.19.1 Business Overview
2.19.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.19.2.1 Product A
2.19.2.2 Product B
2.19.3 Curaxys Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
2.20 ProMetic Life Sciences
2.20.1 Business Overview
2.20.2 Alpha 1 Antitrypsin Deficiency Treatment Type and Applications
2.20.2.1 Product A
2.20.2.2 Product B
2.20.3 ProMetic Life Sciences Alpha 1 Antitrypsin Deficiency Treatment Sales, Price, Revenue, Gross Margin and Market Share (2016-2017)
3 Global Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue, Market Share and Competition by Manufacturer (2016-2017)
3.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales and Market Share by Manufacturer (2016-2017)
3.2 Global Alpha 1 Antitrypsin Deficiency Treatment Revenue and Market Share by Manufacturer (2016-2017)
3.3 Market Concentration Rate
3.3.1 Top 3 Alpha 1 Antitrypsin Deficiency Treatment Manufacturer Market Share in 2017
3.3.2 Top 6 Alpha 1 Antitrypsin Deficiency Treatment Manufacturer Market Share in 2017
3.4 Market Competition Trend
4 Global Alpha 1 Antitrypsin Deficiency Treatment Market Analysis by Regions
4.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue and Market Share by Regions
4.1.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales and Market Share by Regions (2013-2018)
4.1.2 Global Alpha 1 Antitrypsin Deficiency Treatment Revenue and Market Share by Regions (2013-2018)
4.2 North America Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
4.3 Europe Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
4.4 Asia-Pacific Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
4.5 South America Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
4.6 Middle East and Africa Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
5 North America Alpha 1 Antitrypsin Deficiency Treatment by Countries
5.1 North America Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue and Market Share by Countries
5.1.1 North America Alpha 1 Antitrypsin Deficiency Treatment Sales and Market Share by Countries (2013-2018)
5.1.2 North America Alpha 1 Antitrypsin Deficiency Treatment Revenue and Market Share by Countries (2013-2018)
5.2 United States Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
5.3 Canada Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
5.4 Mexico Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
6 Europe Alpha 1 Antitrypsin Deficiency Treatment by Countries
6.1 Europe Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue and Market Share by Countries
6.1.1 Europe Alpha 1 Antitrypsin Deficiency Treatment Sales and Market Share by Countries (2013-2018)
6.1.2 Europe Alpha 1 Antitrypsin Deficiency Treatment Revenue and Market Share by Countries (2013-2018)
6.2 Germany Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
6.3 UK Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
6.4 France Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
6.5 Russia Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
6.6 Italy Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
7 Asia-Pacific Alpha 1 Antitrypsin Deficiency Treatment by Countries
7.1 Asia-Pacific Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue and Market Share by Countries
7.1.1 Asia-Pacific Alpha 1 Antitrypsin Deficiency Treatment Sales and Market Share by Countries (2013-2018)
7.1.2 Asia-Pacific Alpha 1 Antitrypsin Deficiency Treatment Revenue and Market Share by Countries (2013-2018)
7.2 China Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
7.3 Japan Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
7.4 Korea Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
7.5 India Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
7.6 Southeast Asia Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
8 South America Alpha 1 Antitrypsin Deficiency Treatment by Countries
8.1 South America Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue and Market Share by Countries
8.1.1 South America Alpha 1 Antitrypsin Deficiency Treatment Sales and Market Share by Countries (2013-2018)
8.1.2 South America Alpha 1 Antitrypsin Deficiency Treatment Revenue and Market Share by Countries (2013-2018)
8.2 Brazil Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
8.3 Argentina Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
8.4 Colombia Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
9 Middle East and Africa Alpha 1 Antitrypsin Deficiency Treatment by Countries
9.1 Middle East and Africa Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue and Market Share by Countries
9.1.1 Middle East and Africa Alpha 1 Antitrypsin Deficiency Treatment Sales and Market Share by Countries (2013-2018)
9.1.2 Middle East and Africa Alpha 1 Antitrypsin Deficiency Treatment Revenue and Market Share by Countries (2013-2018)
9.2 Saudi Arabia Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
9.3 UAE Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
9.4 Egypt Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
9.5 Nigeria Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
9.6 South Africa Alpha 1 Antitrypsin Deficiency Treatment Sales and Growth Rate (2013-2018)
10 Global Alpha 1 Antitrypsin Deficiency Treatment Market Segment by Type
10.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue and Market Share by Type (2013-2018)
10.1.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales and Market Share by Type (2013-2018)
10.1.2 Global Alpha 1 Antitrypsin Deficiency Treatment Revenue and Market Share by Type (2013-2018)
10.2 Augmentation Therapy Sales Growth and Price
10.2.1 Global Augmentation Therapy Sales Growth (2013-2018)
10.2.2 Global Augmentation Therapy Price (2013-2018)
10.3 Bronchodilators Sales Growth and Price
10.3.1 Global Bronchodilators Sales Growth (2013-2018)
10.3.2 Global Bronchodilators Price (2013-2018)
10.4 Corticosteroids Sales Growth and Price
10.4.1 Global Corticosteroids Sales Growth (2013-2018)
10.4.2 Global Corticosteroids Price (2013-2018)
10.5 Oxygen Therapy Sales Growth and Price
10.5.1 Global Oxygen Therapy Sales Growth (2013-2018)
10.5.2 Global Oxygen Therapy Price (2013-2018)
11 Global Alpha 1 Antitrypsin Deficiency Treatment Market Segment by Application
11.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales Market Share by Application (2013-2018)
11.2 Hospitals Sales Growth (2013-2018)
11.3 Specialty Clinics Sales Growth (2013-2018)
11.4 Pharmacies Sales Growth (2013-2018)
12 Alpha 1 Antitrypsin Deficiency Treatment Market Forecast (2018-2023)
12.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales, Revenue and Growth Rate (2018-2023)
12.2 Alpha 1 Antitrypsin Deficiency Treatment Market Forecast by Regions (2018-2023)
12.2.1 North America Alpha 1 Antitrypsin Deficiency Treatment Market Forecast (2018-2023)
12.2.2 Europe Alpha 1 Antitrypsin Deficiency Treatment Market Forecast (2018-2023)
12.2.3 Asia-Pacific Alpha 1 Antitrypsin Deficiency Treatment Market Forecast (2018-2023)
12.2.4 South America Alpha 1 Antitrypsin Deficiency Treatment Market Forecast (2018-2023)
12.2.5 Middle East and Africa Alpha 1 Antitrypsin Deficiency Treatment Market Forecast (2018-2023)
12.3 Alpha 1 Antitrypsin Deficiency Treatment Market Forecast by Type (2018-2023)
12.3.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales Forecast by Type (2018-2023)
12.3.2 Global Alpha 1 Antitrypsin Deficiency Treatment Market Share Forecast by Type (2018-2023)
12.4 Alpha 1 Antitrypsin Deficiency Treatment Market Forecast by Application (2018-2023)
12.4.1 Global Alpha 1 Antitrypsin Deficiency Treatment Sales Forecast by Application (2018-2023)
12.4.2 Global Alpha 1 Antitrypsin Deficiency Treatment Market Share Forecast by Application (2018-2023)
13 Sales Channel, Distributors, Traders and Dealers
13.1 Sales Channel
13.1.1 Direct Marketing
13.1.2 Indirect Marketing
13.1.3 Marketing Channel Future Trend
13.2 Distributors, Traders and Dealers
14 Research Findings and Conclusion
15 Appendix
15.1 Methodology
15.2 Data Source
List of Tables and Figures
Figure Alpha 1 Antitrypsin Deficiency Treatment Picture
Table Product Specifications of Alpha 1 Antitrypsin Deficiency Treatment
Figure Global Sales Market Share of Alpha 1
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